Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways

OBJECTIVE: Hepatic metabolic disorder induced by lipotoxicity plays a detrimental role in metabolic fatty liver disease pathogenesis. Cimifugin (Cim), a coumarin derivative extracted from the root of Saposhnikovia divaricata, possesses multiple biological properties against inflammation, allergy, an...

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Detalles Bibliográficos
Autores principales: Yang, Wenwen, Zhu, Linwensi, Lai, Shanglei, Ding, Qinchao, Xu, Tiantian, Guo, Rui, Dou, Xiaobing, Chai, Hui, Yu, Zhiling, Li, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958062/
https://www.ncbi.nlm.nih.gov/pubmed/35355867
http://dx.doi.org/10.1155/2022/4557532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958062/
https://www.ncbi.nlm.nih.gov/pubmed/35355867
http://dx.doi.org/10.1155/2022/4557532

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