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Cimifugin Ameliorates Lipotoxicity-Induced Hepatocyte Damage and Steatosis through TLR4/p38 MAPK- and SIRT1-Involved Pathways

OBJECTIVE: Hepatic metabolic disorder induced by lipotoxicity plays a detrimental role in metabolic fatty liver disease pathogenesis. Cimifugin (Cim), a coumarin derivative extracted from the root of Saposhnikovia divaricata, possesses multiple biological properties against inflammation, allergy, an...

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Detalles Bibliográficos
Autores principales:	Yang, Wenwen, Zhu, Linwensi, Lai, Shanglei, Ding, Qinchao, Xu, Tiantian, Guo, Rui, Dou, Xiaobing, Chai, Hui, Yu, Zhiling, Li, Songtao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958062/ https://www.ncbi.nlm.nih.gov/pubmed/35355867 http://dx.doi.org/10.1155/2022/4557532

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