Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage

OBJECTIVE: Mitochondrial damage contributes to extracellular matrix (ECM) deposition and renal fibrosis. In this study, we aimed (1) to investigate whether fluorofenidone (AKF-PD) can attenuate mitochondrial damage in two renal fibrosis models: unilateral ureteral obstruction (UUO) and renal ischemi...

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Detalles Bibliográficos
Autores principales: Liao, Xiaohua, Lv, Xin, Zhang, Yan, Han, Yuanyuan, Li, Jiajia, Zeng, Jianhua, Tang, Damu, Meng, Jie, Yuan, Xiangning, Peng, Zhangzhe, Tao, Lijian, Xie, Yanyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958071/
https://www.ncbi.nlm.nih.gov/pubmed/35355864
http://dx.doi.org/10.1155/2022/2453617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958071/
https://www.ncbi.nlm.nih.gov/pubmed/35355864
http://dx.doi.org/10.1155/2022/2453617

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