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Fluorofenidone Inhibits UUO/IRI-Induced Renal Fibrosis by Reducing Mitochondrial Damage
OBJECTIVE: Mitochondrial damage contributes to extracellular matrix (ECM) deposition and renal fibrosis. In this study, we aimed (1) to investigate whether fluorofenidone (AKF-PD) can attenuate mitochondrial damage in two renal fibrosis models: unilateral ureteral obstruction (UUO) and renal ischemi...
Autores principales: | Liao, Xiaohua, Lv, Xin, Zhang, Yan, Han, Yuanyuan, Li, Jiajia, Zeng, Jianhua, Tang, Damu, Meng, Jie, Yuan, Xiangning, Peng, Zhangzhe, Tao, Lijian, Xie, Yanyun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958071/ https://www.ncbi.nlm.nih.gov/pubmed/35355864 http://dx.doi.org/10.1155/2022/2453617 |
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