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Naloxegol to Prevent Constipation in ICU Adults Receiving Opioids: A Randomized Double-Blind Placebo-Controlled Pilot Trial

BACKGROUND: Constipation is frequent in critically ill adults receiving opioids. Naloxegol (N), a peripherally acting mu-receptor antagonist (PAMORA), may reduce constipation. The objective of this trial was to evaluate the efficacy and safety of N to prevent constipation in ICU adults receiving opi...

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Detalles Bibliográficos
Autores principales: Duprey, Matthew S., Allison, Harmony, Garpestad, Erik, Riselli, Andrew M., Faugno, Anthony, Anketell, Eric, Devlin, John W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958087/
https://www.ncbi.nlm.nih.gov/pubmed/35356796
http://dx.doi.org/10.1155/2022/7541378