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Chromosomal Region 11p14.1 is Associated with Pharmacokinetics and Pharmacodynamics of Bisoprolol

PURPOSE: Bisoprolol is a widely used beta-blocker in patients with cardiovascular diseases. As with other beta-blockers, there is variability in response to bisoprolol, but the underlying reasons for this have not been clearly elucidated. Our aim was to investigate genetic factors that affect bisopr...

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Detalles Bibliográficos
Autores principales: Fontana, Vanessa, Turner, Richard Myles, Francis, Ben, Yin, Peng, Pütz, Benno, Hiltunen, Timo P, Ruotsalainen, Sanni, Kontula, Kimmo K, Müller-Myhsok, Bertam, Pirmohamed, Munir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958266/
https://www.ncbi.nlm.nih.gov/pubmed/35356681
http://dx.doi.org/10.2147/PGPM.S352719