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Glucose and MMP-9 dual-responsive hydrogel with temperature sensitive self-adaptive shape and controlled drug release accelerates diabetic wound healing

Chronic diabetic wounds are an important healthcare challenge. High concentration glucose, high level of matrix metalloproteinase-9 (MMP-9), and long-term inflammation constitute the special wound environment of diabetic wounds. Tissue necrosis aggravates the formation of irregular wounds. All the a...

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Detalles Bibliográficos
Autores principales: Zhou, Wanyi, Duan, Zhiguang, Zhao, Jing, Fu, Rongzhan, Zhu, Chenhui, Fan, Daidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958327/
https://www.ncbi.nlm.nih.gov/pubmed/35386439
http://dx.doi.org/10.1016/j.bioactmat.2022.01.004