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Multi-omics protein-coding units as massively parallel Bayesian networks: Empirical validation of causality structure

In this article we use high-throughput epigenomics, transcriptomics, and proteomics data to construct fine-graded models of the “protein-coding units” gathering all transcript isoforms and chromatin accessibility peaks associated with more than 4000 genes in humans. Each protein-coding unit has the...

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Detalles Bibliográficos
Autores principales: Zenere, Alberto, Rundquist, Olof, Gustafsson, Mika, Altafini, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958332/
https://www.ncbi.nlm.nih.gov/pubmed/35355520
http://dx.doi.org/10.1016/j.isci.2022.104048