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Multi-omics protein-coding units as massively parallel Bayesian networks: Empirical validation of causality structure
In this article we use high-throughput epigenomics, transcriptomics, and proteomics data to construct fine-graded models of the “protein-coding units” gathering all transcript isoforms and chromatin accessibility peaks associated with more than 4000 genes in humans. Each protein-coding unit has the...
Autores principales: | Zenere, Alberto, Rundquist, Olof, Gustafsson, Mika, Altafini, Claudio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958332/ https://www.ncbi.nlm.nih.gov/pubmed/35355520 http://dx.doi.org/10.1016/j.isci.2022.104048 |
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