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The IL‐21‐TET2‐AIM2‐c‐MAF pathway drives the T follicular helper cell response in lupus‐like disease

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that involves T follicular helper (T(FH)) cell‐mediated humoral immune responses. Absent in melanoma 2 (human AIM2 and murine Aim2) is a well‐known component of the inflammasome in the innate immune system. Surprisingly, we observed...

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Detalles Bibliográficos
Autores principales: Wu, Haijing, Deng, Yaxiong, Long, Di, Yang, Ming, Li, Qianwen, Feng, Yu, Chen, Yongjian, Qiu, Hong, Huang, Xin, He, Zhenghao, Hu, Longyuan, Yin, Heng, Li, Guangdi, Guo, Yunkai, Du, Wenhan, Zhao, Ming, Lu, Liwei, Lu, Qianjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958352/
https://www.ncbi.nlm.nih.gov/pubmed/35343082
http://dx.doi.org/10.1002/ctm2.781