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MD2 deficiency prevents high‐fat diet‐induced AMPK suppression and lipid accumulation through regulating TBK1 in non‐alcoholic fatty liver disease

BACKGROUND: Non‐alcoholic fatty liver disease (NAFLD) is the most predominant form of liver diseases worldwide. Recent evidence shows that myeloid differentiation factor 2 (MD2), a protein in innate immunity and inflammation, regulates liver injury in models of NAFLD. Here, we investigated a new mec...

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Detalles Bibliográficos
Autores principales: Luo, Wu, Ye, Lin, Hu, Xue‐ting, Wang, Mei‐hong, Wang, Min‐xiu, Jin, Lei‐ming, Xiao, Zhong‐xiang, Qian, Jian‐chang, Wang, Yi, Zuo, Wei, Huang, Li‐jiang, Liang, Guang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958353/
https://www.ncbi.nlm.nih.gov/pubmed/35343085
http://dx.doi.org/10.1002/ctm2.777