Polymersome-mediated cytosolic delivery of cyclic dinucleotide STING agonist enhances tumor immunotherapy

Cyclic dinucleotides (CDNs) as stimulator of interferon genes (STING) agonists capable of inducing strong antitumor innate immune response are highly promising for tumor immunotherapy. The efficacy of these CDNs is, however, reduced greatly by their fast clearance, poor cell uptake and inefficient c...

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Detalles Bibliográficos
Autores principales: Zheng, Huan, Guo, Beibei, Qiu, Xinyun, Xia, Yifeng, Qu, Yan, Cheng, Liang, Meng, Fenghua, Zhong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958419/
https://www.ncbi.nlm.nih.gov/pubmed/35386324
http://dx.doi.org/10.1016/j.bioactmat.2022.02.029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958419/
https://www.ncbi.nlm.nih.gov/pubmed/35386324
http://dx.doi.org/10.1016/j.bioactmat.2022.02.029

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