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Remodeling tumor immunosuppressive microenvironment via a novel bioactive nanovaccines potentiates the efficacy of cancer immunotherapy

The clinical outcomes of cancer nanovaccine have been largely impeded owing to the low antigen-specific T cell response rate and acquired resistance caused by the immunosuppressive tumor microenvironment (TME). Here, we reported a tumor acidity-responsive nanovaccine to remodel the immunosuppressive...

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Detalles Bibliográficos
Autores principales: Xie, Xiaoxue, Feng, Yi, Zhang, Hanxi, Su, Qingqing, Song, Ting, Yang, Geng, Li, Ningxi, Wei, Xiaodan, Li, Tingting, Qin, Xiang, Li, Shun, Wu, Chunhui, Zhang, Xiaojuan, Wang, Guixue, Liu, Yiyao, Yang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958467/
https://www.ncbi.nlm.nih.gov/pubmed/35386322
http://dx.doi.org/10.1016/j.bioactmat.2022.03.008