Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors

[Image: see text] Photopharmacology uses light to regulate the biological activity of drugs. This precise control is obtained through the incorporation of molecular photoswitches into bioactive molecules. A major challenge for photopharmacology is the rational design of photoswitchable drugs that sh...

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Detalles Bibliográficos
Autores principales: Kobauri, Piermichele, Galenkamp, Nicole S., Schulte, Albert M., de Vries, Jisk, Simeth, Nadja A., Maglia, Giovanni, Thallmair, Sebastian, Kolarski, Dušan, Szymanski, Wiktor, Feringa, Ben L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958501/
https://www.ncbi.nlm.nih.gov/pubmed/35258959
http://dx.doi.org/10.1021/acs.jmedchem.1c01962

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958501/
https://www.ncbi.nlm.nih.gov/pubmed/35258959
http://dx.doi.org/10.1021/acs.jmedchem.1c01962

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