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Hypothesis-Driven, Structure-Based Design in Photopharmacology: The Case of eDHFR Inhibitors
[Image: see text] Photopharmacology uses light to regulate the biological activity of drugs. This precise control is obtained through the incorporation of molecular photoswitches into bioactive molecules. A major challenge for photopharmacology is the rational design of photoswitchable drugs that sh...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958501/ https://www.ncbi.nlm.nih.gov/pubmed/35258959 http://dx.doi.org/10.1021/acs.jmedchem.1c01962 |