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G-Quadruplex DNA as a Target in Pathogenic Bacteria: Efficacy of an Extended Naphthalene Diimide Ligand and Its Mode of Action

[Image: see text] Guanidine DNA quadruplex (G4-DNA) structures convey a distinctive layer of epigenetic information that is critical for regulating key biological activities and processes as transcription, replication, and repair in living cells. The information regarding their role and use as thera...

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Detalles Bibliográficos
Autores principales: Cebrián, Rubén, Belmonte-Reche, Efres, Pirota, Valentina, de Jong, Anne, Morales, Juan Carlos, Freccero, Mauro, Doria, Filippo, Kuipers, Oscar P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958502/
https://www.ncbi.nlm.nih.gov/pubmed/34928608
http://dx.doi.org/10.1021/acs.jmedchem.1c01905