Dynamic Combinatorial Optimization of In Vitro and In Vivo Heparin Antidotes

[Image: see text] Heparin-like macromolecules are widely used in clinics as anticoagulant, antiviral, and anticancer drugs. However, the search of heparin antidotes based on small synthetic molecules to control blood coagulation still remains a challenging task due to the physicochemical properties...

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Detalles Bibliográficos
Autores principales: Carbajo, Daniel, Pérez, Yolanda, Guerra-Rebollo, Marta, Prats, Eva, Bujons, Jordi, Alfonso, Ignacio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958503/
https://www.ncbi.nlm.nih.gov/pubmed/35235323
http://dx.doi.org/10.1021/acs.jmedchem.1c02054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958503/
https://www.ncbi.nlm.nih.gov/pubmed/35235323
http://dx.doi.org/10.1021/acs.jmedchem.1c02054

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