Exacerbated Renal and Hematologic Toxicities to Ifosfamide and Doxorubicin-Based Chemotherapy in a Patient with Retroperitoneal Liposarcoma Harboring a Germline Mutation in the WRN Gene

Werner's syndrome is caused by the inactivation of both WRN alleles and is characterized by premature aging and increased risk of neoplasms, especially those of mesenchymal origins, such as sarcomas. Given the characteristic genomic instability, patients with this syndrome are more susceptible...

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Detalles Bibliográficos
Autores principales: Awni, Beatriz Mendes, Holanda Lopes, Carlos Diego, Harada, Guilherme, Salgues, Alessandra Corte Real, França, Gilmar de Andrade, Testagrossa, Leonardo de Abreu, Queiroz, Marcelo Araujo, Gonçalves e Silva, Adriano, Ferreira, Fabio de Oliveira, Munhoz, Rodrigo Ramella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958610/
https://www.ncbi.nlm.nih.gov/pubmed/35431856
http://dx.doi.org/10.1159/000521624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958610/
https://www.ncbi.nlm.nih.gov/pubmed/35431856
http://dx.doi.org/10.1159/000521624

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