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Bone Marrow Mononuclear Cells Restore Normal Mitochondrial Ca(2+) Handling and Ca(2+)-Induced Depolarization of the Internal Mitochondrial Membrane by Inhibiting the Permeability Transition Pore After Ischemia/Reperfusion

Acute kidney injury due to ischemia followed by reperfusion (IR) is a severe clinical condition with high death rates. IR affects the proximal tubule segments due to their predominantly oxidative metabolism and profoundly altered mitochondrial functions. We previously described the impact of IR on o...

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Detalles Bibliográficos
Autores principales: Rodrigues-Ferreira, Clara, Lopes, Jarlene Alécia, Carneiro, Priscila Fonseca, dos Santos Lessa, Cristiane, Galina, Antonio, Vieyra, Adalberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958683/
https://www.ncbi.nlm.nih.gov/pubmed/35343271
http://dx.doi.org/10.1177/09636897221085883