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Molnupiravir; molecular and functional descriptors of mitochondrial safety

Molnupiravir is an orally active nucleoside analog antiviral drug that recently was approved by the U.S. FDA for emergency treatment of adult patients infected with the SARS-CoV-2 (COVID-19) virus and at risk for severe progression. The active form of the drug, N-hydroxycytidine (NHC) triphosphate c...

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Detalles Bibliográficos
Autores principales: Wallace, K.B., Bjork, J.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958731/
https://www.ncbi.nlm.nih.gov/pubmed/35358570
http://dx.doi.org/10.1016/j.taap.2022.116003