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Proteolytic inhibitors as alternative medicines to treat trypanosomatid-caused diseases: experience with calpain inhibitors

The treatment for tropical neglected diseases, such as Chagas disease (CD) and leishmaniasis, is extremely limited to a handful of drugs that suffer from unacceptable toxicity, tough administration routes, like parenteral, and increasing treatment failures due to the parasite resistance. Consequentl...

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Detalles Bibliográficos
Autores principales: Ennes-Vidal, Vítor, dos Santos, André Luis Souza, Branquinha, Marta Helena, d’Avila-Levy, Claudia Masini
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958894/
https://www.ncbi.nlm.nih.gov/pubmed/35352772
http://dx.doi.org/10.1590/0074-02760220017