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Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients in the intensive care unit

Accumulating evidence proves that endothelial dysfunction is involved in coronavirus disease 2019 (COVID-19) progression. We previously demonstrated that the endothelial surface glycocalyx has a critical role in maintenance of vascular integrity. Here, we hypothesised that serum factors of severe CO...

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Detalles Bibliográficos
Autores principales: Yuan, Lushun, Cheng, Shuzhen, Sol, Wendy M.P.J., van der Velden, Anouk I.M., Vink, Hans, Rabelink, Ton J., van den Berg, Bernard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Respiratory Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958944/
https://www.ncbi.nlm.nih.gov/pubmed/35509442
http://dx.doi.org/10.1183/23120541.00652-2021