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Heparan sulfate mimetic fucoidan restores the endothelial glycocalyx and protects against dysfunction induced by serum of COVID-19 patients in the intensive care unit
Accumulating evidence proves that endothelial dysfunction is involved in coronavirus disease 2019 (COVID-19) progression. We previously demonstrated that the endothelial surface glycocalyx has a critical role in maintenance of vascular integrity. Here, we hypothesised that serum factors of severe CO...
Autores principales: | Yuan, Lushun, Cheng, Shuzhen, Sol, Wendy M.P.J., van der Velden, Anouk I.M., Vink, Hans, Rabelink, Ton J., van den Berg, Bernard M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
European Respiratory Society
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958944/ https://www.ncbi.nlm.nih.gov/pubmed/35509442 http://dx.doi.org/10.1183/23120541.00652-2021 |
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