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A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning

[Image: see text] Recent events demonstrated that organophosphorus nerve agents are a serious threat for civilian and military populations. The current therapy includes a pyridinium aldoxime reactivator to restore the enzymatic activity of acetylcholinesterase located in the central nervous system a...

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Detalles Bibliográficos
Autores principales: Da Silva, Ophélie, Probst, Nicolas, Landry, Christophe, Hanak, Anne-Sophie, Warnault, Pierre, Coisne, Caroline, Calas, André-Guilhem, Gosselet, Fabien, Courageux, Charlotte, Gastellier, Anne-Julie, Trancart, Marilène, Baati, Rachid, Dehouck, Marie-Pierre, Jean, Ludovic, Nachon, Florian, Renard, Pierre-Yves, Dias, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8958973/
https://www.ncbi.nlm.nih.gov/pubmed/35255209
http://dx.doi.org/10.1021/acs.jmedchem.1c01748