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Differential viral RNA methylation contributes to pathogen blocking in Wolbachia-colonized arthropods

Arthropod endosymbiont Wolbachia pipientis is part of a global biocontrol strategy to reduce the replication of mosquito-borne RNA viruses such as alphaviruses. We previously demonstrated the importance of a host cytosine methyltransferase, DNMT2, in Drosophila and viral RNA as a cellular target dur...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Tamanash, Yan, Liewei, Crawford, John M., Zaher, Hani, Newton, Irene L. G., Hardy, Richard W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959158/
https://www.ncbi.nlm.nih.gov/pubmed/35294495
http://dx.doi.org/10.1371/journal.ppat.1010393