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Cytosolic O-GlcNAcylation and PNG1 maintain Drosophila gut homeostasis by regulating proliferation and apoptosis

Tissue homeostasis requires a delicate balance between stem cell self-renewal, proliferation, and differentiation. Essential to this process is glycosylation, with both intra-and extra-cellular glycosylation being required for stem cell homeostasis. However, it remains unknown how intracellular glyc...

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Detalles Bibliográficos
Autores principales: Na, Hyun-jin, Abramowitz, Lara K., Hanover, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959174/
https://www.ncbi.nlm.nih.gov/pubmed/35294432
http://dx.doi.org/10.1371/journal.pgen.1010128