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MurA escape mutations uncouple peptidoglycan biosynthesis from PrkA signaling

Gram-positive bacteria are protected by a thick mesh of peptidoglycan (PG) completely engulfing their cells. This PG network is the main component of the bacterial cell wall, it provides rigidity and acts as foundation for the attachment of other surface molecules. Biosynthesis of PG consumes a high...

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Detalles Bibliográficos
Autores principales: Wamp, Sabrina, Rothe, Patricia, Stern, Daniel, Holland, Gudrun, Döhling, Janina, Halbedel, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959180/
https://www.ncbi.nlm.nih.gov/pubmed/35294506
http://dx.doi.org/10.1371/journal.ppat.1010406