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Experimental evolution links post-transcriptional regulation to Leishmania fitness gain

The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genome instability generates beneficial phenotypes desp...

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Detalles Bibliográficos
Autores principales: Piel, Laura, Rajan, K. Shanmugha, Bussotti, Giovanni, Varet, Hugo, Legendre, Rachel, Proux, Caroline, Douché, Thibaut, Giai-Gianetto, Quentin, Chaze, Thibault, Cokelaer, Thomas, Vojtkova, Barbora, Gordon-Bar, Nadav, Doniger, Tirza, Cohen-Chalamish, Smadar, Rengaraj, Praveenkumar, Besse, Céline, Boland, Anne, Sadlova, Jovana, Deleuze, Jean-François, Matondo, Mariette, Unger, Ron, Volf, Petr, Michaeli, Shulamit, Pescher, Pascale, Späth, Gerald F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959184/
https://www.ncbi.nlm.nih.gov/pubmed/35294501
http://dx.doi.org/10.1371/journal.ppat.1010375