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Experimental evolution links post-transcriptional regulation to Leishmania fitness gain
The protozoan parasite Leishmania donovani causes fatal human visceral leishmaniasis in absence of treatment. Genome instability has been recognized as a driver in Leishmania fitness gain in response to environmental change or chemotherapy. How genome instability generates beneficial phenotypes desp...
Autores principales: | Piel, Laura, Rajan, K. Shanmugha, Bussotti, Giovanni, Varet, Hugo, Legendre, Rachel, Proux, Caroline, Douché, Thibaut, Giai-Gianetto, Quentin, Chaze, Thibault, Cokelaer, Thomas, Vojtkova, Barbora, Gordon-Bar, Nadav, Doniger, Tirza, Cohen-Chalamish, Smadar, Rengaraj, Praveenkumar, Besse, Céline, Boland, Anne, Sadlova, Jovana, Deleuze, Jean-François, Matondo, Mariette, Unger, Ron, Volf, Petr, Michaeli, Shulamit, Pescher, Pascale, Späth, Gerald F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959184/ https://www.ncbi.nlm.nih.gov/pubmed/35294501 http://dx.doi.org/10.1371/journal.ppat.1010375 |
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