Activation of NLRP3 Inflammasome by Virus-Like Particles of Human Polyomaviruses in Macrophages

Viral antigens can activate phagocytes, inducing inflammation, but the mechanisms are barely explored. The aim of this study is to investigate how viral oligomeric proteins of different structures induce inflammatory response in macrophages. Human THP-1 cell line was used to prepare macrophages that...

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Detalles Bibliográficos
Autores principales: Lučiūnaitė, Asta, Dalgėdienė, Indrė, Žilionis, Rapolas, Mašalaitė, Kristina, Norkienė, Milda, Šinkūnas, Andrius, Gedvilaitė, Alma, Kučinskaitė-Kodzė, Indrė, Žvirblienė, Aurelija
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959312/
https://www.ncbi.nlm.nih.gov/pubmed/35355981
http://dx.doi.org/10.3389/fimmu.2022.831815

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959312/
https://www.ncbi.nlm.nih.gov/pubmed/35355981
http://dx.doi.org/10.3389/fimmu.2022.831815

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