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Activation of NLRP3 Inflammasome by Virus-Like Particles of Human Polyomaviruses in Macrophages
Viral antigens can activate phagocytes, inducing inflammation, but the mechanisms are barely explored. The aim of this study is to investigate how viral oligomeric proteins of different structures induce inflammatory response in macrophages. Human THP-1 cell line was used to prepare macrophages that...
Autores principales: | Lučiūnaitė, Asta, Dalgėdienė, Indrė, Žilionis, Rapolas, Mašalaitė, Kristina, Norkienė, Milda, Šinkūnas, Andrius, Gedvilaitė, Alma, Kučinskaitė-Kodzė, Indrė, Žvirblienė, Aurelija |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959312/ https://www.ncbi.nlm.nih.gov/pubmed/35355981 http://dx.doi.org/10.3389/fimmu.2022.831815 |
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