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Antigen-Specific TCR-T Cells for Acute Myeloid Leukemia: State of the Art and Challenges
The cytogenetic abnormalities and molecular mutations involved in acute myeloid leukemia (AML) lead to unique treatment challenges. Although adoptive T-cell therapies (ACT) such as chimeric antigen receptor (CAR) T-cell therapy have shown promising results in the treatment of leukemias, especially B...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959347/ https://www.ncbi.nlm.nih.gov/pubmed/35356211 http://dx.doi.org/10.3389/fonc.2022.787108 |