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Isolevuglandins Scavenger Ameliorates Myocardial Ischemic Injury by Suppressing Oxidative Stress, Apoptosis, and Inflammation

Augmented levels of reactive isolevuglandins (IsoLGs) are responsible for cardiovascular diseases. The role of IsoLGs in myocardial infarction (MI) remains elusive. Here we explored the effect of IsoLGs scavenger 2-hydroxybenzylamine (2-HOBA) in post-infarction cardiac repair. We observed that infar...

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Detalles Bibliográficos
Autores principales: Guo, Junjie, Xu, Fengqiang, Ji, Hongwei, Jing, Yajun, Shen, Li, Weng, Xinyu, Hu, Longgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959416/
https://www.ncbi.nlm.nih.gov/pubmed/35356291
http://dx.doi.org/10.3389/fcell.2022.836035