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Molecular Characterization of Differentiated-Resistance MSC Subclones by Single-Cell Transcriptomes

Background: The mechanism of tumorigenicity potentially evolved in mesenchymal stem cells (MSCs) remains elusive, resulting in inconsistent clinical application efficacy. We hypothesized that subclones in MSCs contribute to their tumorgenicity, and we approached MSC-subclones at the single-cell leve...

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Detalles Bibliográficos
Autores principales: Stucky, Andres, Gao, Li, Li, Shengwen Calvin, Tu, Lingli, Luo, Jun, Huang, Xi, Chen, Xuelian, Li, Xiaoqing, Park, Tiffany H., Cai, Jin, Kabeer, Mustafa H., Plant, Ashley S., Sun, Lan, Zhang, Xi, Zhong, Jiang F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959432/
https://www.ncbi.nlm.nih.gov/pubmed/35356283
http://dx.doi.org/10.3389/fcell.2022.699144