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Suitability of transiently expressed antibodies for clinical studies: product quality consistency at different production scales

Transgenic human monoclonal antibodies derived from humanized mice against different epitopes of the Middle East respiratory syndrome coronavirus (MERS-CoV), and chimeric llama-human bispecific heavy chain-only antibodies targeting the Rift Valley fever virus (RVFV), were produced using a CHO-based...

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Detalles Bibliográficos
Autores principales: Rodriguez-Conde, Sara, Inman, Sophie, Lindo, Viv, Amery, Leanne, Tang, Alison, Okorji-Obike, Uche, Du, Wenjuan, Bosch, Berend-Jan, Wichgers Schreur, Paul J., Kortekaas, Jeroen, Sola, Isabel, Enjuanes, Luis, Kerry, Laura, Mahal, Katharina, Hulley, Martyn, Daramola, Olalekan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959507/
https://www.ncbi.nlm.nih.gov/pubmed/35323099
http://dx.doi.org/10.1080/19420862.2022.2052228