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Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells

Approximately 40% of patients with diffuse large B-cell lymphoma (DLBCL) are refractory or relapse to standard chemotherapy, and most of them are activated B cell-like DLBCLs (ABC-DLBCL) and germinal center B cell-like DLBCLs (GCB-DLBCL). SNS-032, a novel and selective CDK7/9 inhibitor, that the fir...

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Detalles Bibliográficos
Autores principales: Jiang, Liling, Wen, Chuangyu, Zhou, Huan, Liu, Aochu, Zhang, Haichuan, Chen, Xinmei, Ding, Wa, Liu, Jinbao, Shi, Xianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959513/
https://www.ncbi.nlm.nih.gov/pubmed/35332847
http://dx.doi.org/10.1080/15384047.2022.2055421