Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies

Cancer immunotherapy strategies based on the endogenous secretion of T cell-redirecting bispecific antibodies by engineered T lymphocytes (STAb-T) are emerging as alternative or complementary approaches to those based on chimeric antigen receptors (CAR-T). The antitumor efficacy of bispecific anti-C...

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Detalles Bibliográficos
Autores principales: Ramírez-Fernández, Ángel, Aguilar-Sopeña, Óscar, Díez-Alonso, Laura, Segura-Tudela, Alejandro, Domínguez-Alonso, Carmen, Roda-Navarro, Pedro, Álvarez-Vallina, Luis, Blanco, Belén
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959521/
https://www.ncbi.nlm.nih.gov/pubmed/35355682
http://dx.doi.org/10.1080/2162402X.2022.2054106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959521/
https://www.ncbi.nlm.nih.gov/pubmed/35355682
http://dx.doi.org/10.1080/2162402X.2022.2054106

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