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Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies
Cancer immunotherapy strategies based on the endogenous secretion of T cell-redirecting bispecific antibodies by engineered T lymphocytes (STAb-T) are emerging as alternative or complementary approaches to those based on chimeric antigen receptors (CAR-T). The antitumor efficacy of bispecific anti-C...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959521/ https://www.ncbi.nlm.nih.gov/pubmed/35355682 http://dx.doi.org/10.1080/2162402X.2022.2054106 |