YAP1 activation by human papillomavirus E7 promotes basal cell identity in squamous epithelia

Persistent human papillomavirus (HPV) infection of stratified squamous epithelial cells causes nearly 5% of cancer cases worldwide. HPV-positive oropharyngeal cancers harbor few mutations in the Hippo signaling pathway compared to HPV-negative cancers at the same anatomical site, prompting the hypot...

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Detalles Bibliográficos
Autores principales: Hatterschide, Joshua, Castagnino, Paola, Kim, Hee Won, Sperry, Steven M, Montone, Kathleen T, Basu, Devraj, White, Elizabeth A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959598/
https://www.ncbi.nlm.nih.gov/pubmed/35170430
http://dx.doi.org/10.7554/eLife.75466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959598/
https://www.ncbi.nlm.nih.gov/pubmed/35170430
http://dx.doi.org/10.7554/eLife.75466

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