Critical role for isoprenoids in apicoplast biogenesis by malaria parasites

Isopentenyl pyrophosphate (IPP) is an essential metabolic output of the apicoplast organelle in Plasmodium falciparum malaria parasites and is required for prenylation-dependent vesicular trafficking and other cellular processes. We have elucidated a critical and previously uncharacterized role for...

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Detalles Bibliográficos
Autores principales: Okada, Megan, Rajaram, Krithika, Swift, Russell P, Mixon, Amanda, Maschek, John Alan, Prigge, Sean T, Sigala, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959605/
https://www.ncbi.nlm.nih.gov/pubmed/35257658
http://dx.doi.org/10.7554/eLife.73208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959605/
https://www.ncbi.nlm.nih.gov/pubmed/35257658
http://dx.doi.org/10.7554/eLife.73208

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