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Targeting Integrins for Cancer Therapy - Disappointments and Opportunities
Integrins mediate adhesive interactions between cells and their environment, including neighboring cells and extracellular matrix (ECM). These heterodimeric transmembrane receptors bind extracellular ligands with their globular head domains and connect to the cytoskeleton through multi-protein inter...
Autores principales: | Bergonzini, Cecilia, Kroese, Kim, Zweemer, Annelien J. M., Danen, Erik H. J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959606/ https://www.ncbi.nlm.nih.gov/pubmed/35356286 http://dx.doi.org/10.3389/fcell.2022.863850 |
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