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Heterologous Immune Responses of Serum IgG and Secretory IgA Against the Spike Protein of Endemic Coronaviruses During Severe COVID-19

Defining immune correlates of disease severity is important to better understand the immunopathogenesis in COVID-19. Here we made use of a protein microarray platform to detect IgG- and IgA-reactive antibodies in sera and saliva respectively, and assess cross-reactivity between SARS-CoV-2 and endemi...

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Detalles Bibliográficos
Autores principales: Smit, Wouter L., van Tol, Sophie, van der Wal, Sanne, van Vulpen, Femke, la Grouw, Shannon, van Lelyveld, Lenneke, Limonard, Gijs, Bossink, Ailko, Godeke, Gert-Jan, Shrestha, Sandhya, Reimerink, Johan, Eggink, Dirk, Reusken, Chantal, Heron, Michiel, Thijsen, Steven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959642/
https://www.ncbi.nlm.nih.gov/pubmed/35355988
http://dx.doi.org/10.3389/fimmu.2022.839367