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Population balance modelling captures host cell protein dynamics in CHO cell cultures
Monoclonal antibodies (mAbs) have been extensively studied for their wide therapeutic and research applications. Increases in mAb titre has been achieved mainly by cell culture media/feed improvement and cell line engineering to increase cell density and specific mAb productivity. However, this impr...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959726/ https://www.ncbi.nlm.nih.gov/pubmed/35320326 http://dx.doi.org/10.1371/journal.pone.0265886 |