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Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway

Tissue remodeling/fibrosis is a main feature of idiopathic pulmonary fibrosis (IPF), which results in the replacement of normal lung parenchyma with a collagen-rich extracellular matrix produced by fibroblasts and myofibroblasts. Epithelial-mesenchymal transition (EMT) in type 2 lung epithelial cell...

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Detalles Bibliográficos
Autores principales: Hu, Xingxing, Zou, Menglin, Ni, Lan, Zhang, Mingyang, Zheng, Weishuai, Liu, Bing, Cheng, Zhenshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959854/
https://www.ncbi.nlm.nih.gov/pubmed/35355710
http://dx.doi.org/10.3389/fphar.2022.829673