T-Cell Responses to Immunodominant Listeria Epitopes Limit Vaccine-Directed Responses to the Colorectal Cancer Antigen, Guanylyl Cyclase C

The Gram-positive bacterium Listeria monocytogenes (Lm) is an emerging platform for cancer immunotherapy. To date, over 30 clinical trials have been initiated testing Lm cancer vaccines across a wide variety of cancers, including lung, cervical, colorectal, and pancreatic. Here, we assessed the immu...

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Detalles Bibliográficos
Autores principales: Flickinger, John C., Singh, Jagmohan, Yarman, Yanki, Carlson, Robert D., Barton, Joshua R., Waldman, Scott A., Snook, Adam E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959893/
https://www.ncbi.nlm.nih.gov/pubmed/35355987
http://dx.doi.org/10.3389/fimmu.2022.855759

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8959893/
https://www.ncbi.nlm.nih.gov/pubmed/35355987
http://dx.doi.org/10.3389/fimmu.2022.855759

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