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Staphylococcus aureus Multiplexes Death-Effector Deoxyribonucleosides to Neutralize Phagocytes

Adenosine synthase A (AdsA) is a key virulence factor of Staphylococcus aureus, a dangerous microbe that causes fatal diseases in humans. Together with staphylococcal nuclease, AdsA generates deoxyadenosine (dAdo) from neutrophil extracellular DNA traps thereby igniting caspase-3-dependent cell deat...

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Detalles Bibliográficos
Autores principales: Tantawy, Eshraq, Schwermann, Nicoletta, Ostermeier, Tjorven, Garbe, Annette, Bähre, Heike, Vital, Marius, Winstel, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960049/
https://www.ncbi.nlm.nih.gov/pubmed/35355997
http://dx.doi.org/10.3389/fimmu.2022.847171