Overexpression of the Hsa21 Transcription Factor RUNX1 Modulates the Extracellular Matrix in Trisomy 21 Cells

Down syndrome is a neurodevelopmental disorder frequently characterized by other developmental defects, such as congenital heart disease. Analysis of gene expression profiles of hearts from trisomic fetuses have shown upregulation of extracellular matrix (ECM) genes. The aim of this work was to iden...

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Detalles Bibliográficos
Autores principales: Mollo, Nunzia, Aurilia, Miriam, Scognamiglio, Roberta, Zerillo, Lucrezia, Cicatiello, Rita, Bonfiglio, Ferdinando, Pagano, Pasqualina, Paladino, Simona, Conti, Anna, Nitsch, Lucio, Izzo, Antonella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960062/
https://www.ncbi.nlm.nih.gov/pubmed/35356434
http://dx.doi.org/10.3389/fgene.2022.824922

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960062/
https://www.ncbi.nlm.nih.gov/pubmed/35356434
http://dx.doi.org/10.3389/fgene.2022.824922

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