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Microglia-Specific Promoter Activities of HEXB Gene

Adeno-associated virus (AAV)-mediated genetic targeting of microglia remains a challenge. Overcoming this hurdle is essential for gene editing in the central nervous system (CNS). Here, we characterized the minimal/native promoter of the HEXB gene, which is known to be specifically and stably expres...

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Detalles Bibliográficos
Autores principales: Shah, Sahil, Wong, Lilly M., Ellis, Kendra, Bodnar, Brittany, Saribas, Sami, Ting, Julia, Wei, Zhengyu, Tang, Yuyang, Wang, Xianwei, Wang, Hong, Ling, Binhua, Margolis, David M., Garcia, J. Victor, Hu, Wenhui, Jiang, Guochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960132/
https://www.ncbi.nlm.nih.gov/pubmed/35360489
http://dx.doi.org/10.3389/fncel.2022.808598