Environmental exposures associated with elevated risk for autism spectrum disorder may augment the burden of deleterious de novo mutations among probands

Although the full aetiology of autism spectrum disorder (ASD) is unknown, familial and twin studies demonstrate high heritability of 60–90%, indicating a predominant role of genetics in the development of the disorder. The genetic architecture of ASD consists of a complex array of rare and common va...

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Detalles Bibliográficos
Autores principales: Pugsley, Kealan, Scherer, Stephen W., Bellgrove, Mark A., Hawi, Ziarih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Expert Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960415/
https://www.ncbi.nlm.nih.gov/pubmed/34002022
http://dx.doi.org/10.1038/s41380-021-01142-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960415/
https://www.ncbi.nlm.nih.gov/pubmed/34002022
http://dx.doi.org/10.1038/s41380-021-01142-w

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