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Celastrol Alleviates Autoimmune Hepatitis Through the PI3K/AKT Signaling Pathway Based on Network Pharmacology and Experiments

Objective: This work aims to explore the potential targets and underlying therapeutic mechanisms of celastrol in autoimmune hepatitis (AIH) through network pharmacology and experiments on Laboratory Animals. Methods: A drug-target interaction network was constructed to predict the possible targets o...

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Detalles Bibliográficos
Autores principales: Wang, Shuhui, Huang, Zheng, Lei, Yu, Han, Xu, Tian, Dean, Gong, Jin, Liu, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8960436/
https://www.ncbi.nlm.nih.gov/pubmed/35359864
http://dx.doi.org/10.3389/fphar.2022.816350